Ribosome biogenesis disruption mediated chromatin structure changes revealed by SRAtac, a customizable end to end analysis pipeline for ATAC-seq

Abstract The nucleolus is a large nuclear body that serves as the primary site for ribosome biogenesis.Recent studies have suggested that it also plays an important role in organizing chromatin architecture.However, to establish a causal relationship between nucleolar ribosome assembly and Eye chromatin architecture, genetic tools are required to d

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Mechanisms for the prevention of adolescent intimate partner violence: A realist review of interventions in low- and middle-income countries.

Adolescent girls are among those at the greatest risk of experiencing intimate partner violence (IPV).Despite adolescence being widely regarded as a window of opportunity to influence attitudes and behaviours related to gender equality, evidence on what works to prevent IPV at this critical stage is limited outside of high-income, school-based sett

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AED Inequity among Social Groups in Guangzhou

Automated external defibrillators (AEDs) are regarded as the most important public facility after fire extinguishers due to their importance to out-of-hospital cardiac arrest (OHCA) victims.Previous studies focused on the location optimization of the AED, with little attention to inequity among different social groups.To comprehensively investigate

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